The Tigers (1-2 overall, 1-0 SWAC) got a 79-yard punt return by Route to give Grambling State a quick 7-0 lead with 10:32 remaining in the opening quarter.
Grambling State extended the lead to 14-0 when Aldon Clark scored on an 11-yard with 5:56 left and on the very next the Alabama State drive, Christmas returned a deflected Darryl Pearson pass 66 yards for a touchdown as the Tigers built a 21-0 advantage through one quarter.
Marc Orozco, who came into the game 44 points shy of becoming the all-time leader in points by a kicker, booted the first of two field goals, a 21-yarder, to extend the lead to 24-0 with 6:39 left in the first half. He connected on a 29-yard field goal with 1:24 remaining in the third quarter to push the margin to 27-0.
Midway through the final quarter, Geremy Hickbottom completed a pass to Kobe Ross and he was stripped of the football and Devohn Lindsey fell on it in the end zone to give the Tigers a 34-0 advantage.